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How Ozempic works: why a diabetes shot makes people stop feeling hungry

The first drug of the Ozempic family came from the venom of a desert lizard. These drugs were made for diabetes, and the people who took them also lost weight. Here is the gut hormone they copy, GLP-1, and how a weekly shot reaches the parts of the brain that decide when you are full. Then the questions people ask most: what happens when you stop, why the weight comes back, why the pens ran out, the nausea, how much weight the big trials found, tirzepatide (Mounjaro and Zepbound), and what the drug does for the heart.