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Previous episode Moles: most carry a cancer mutation, so why do they stop growing?

How cancer starts: how a normal cell turns into cancer

p53: the gene that tells a damaged cell to destroy itself

An elephant has far more cells than you, so it should get cancer far more often. It gets it less. The clue is a gene you carry too, the brake that is broken in more cancers than any other.

  1. 1 A cell has a whole team of brakes. The most famous one is a gene called p53. It is broken in more cancers than any other gene.p53

    A cell has a whole team of brakes. The most famous one is a gene called p53. It is broken in more cancers than any other gene.

  2. 2 p53 watches the DNA. When the DNA is damaged, p53 presses the brake. The cell stops copying and gets time to repair the damage.damaged DNAp53

    p53 watches the DNA. When the DNA is damaged, p53 presses the brake. The cell stops copying and gets time to repair the damage.

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Next episode Why cancer risk rises with age: one cell needs several mutations

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